rs5443, CDCA3;GNB3

N. diseases: 106
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE The present study suggests no major involvement of the GNB3 825C>T polymorphism in components of the metabolic syndrome. 16284746 2006
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE The Gly972Arg and C825T polymorphisms are associated neither with PCOS nor with metabolic syndrome in the Slovak female population. 20170352 2010
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE The C825T polymorphism in the gene coding for the beta3 subunit of G proteins (GNB3) has been shown to be associated with several phenotypes such as hypertension, obesity, and diabetes mellitus comprising the metabolic syndrome. 15033462 2004
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE Clinically silent adrenal adenomas - their relation to the metabolic syndrome and to GNB3 C825T gene polymorphism. 21979884 2011
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE AGT T174M, GNB3 825C>T, and APOC3 -455T>C genotypes were significantly associated with MetS (P = 0.018, 0.0056, and 0.029, respectively) for female adults, whereas FABP2 A54T genotype was associated with MetS (P = 0.040) for female adolescents. 15869758 2006
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.060 GeneticVariation BEFREE A common 825C>T polymorphism in exon 10 of the gene for the beta-3 subunit of heterotrimeric G-proteins, GNB3, has been associated in some studies with traits of the metabolic syndrome as well as coronary artery disease (CAD), but these associations were refuted by other studies. 16908025 2007